PROJECTS

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Next gen sequencing

RNA-seq and bioinformatic analysis

Behavioural assays for disease models of MDD & MAD

A guide to how I share code for scientific work.

Cortical cell culturing and flourecent imaging

Intrinsic and extrinsic calibration examples from 3D photogrammetry.

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Cell staining techniques

Golgi-Cox, immunofluorescence.

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Low-cost facial expression in mice

Raspberry Pi cameras for high quality results.

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What comes after DeepLabCut: Open Field Test edition

Simple code for turning DeepLabCut outputs into meaningful results and publishable figures.

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Mouse gait analysis

Levaraging deep learning for studying mouse gait

Biocoders co-founder

Supporting researchers developing coding skills at Carleton University and the University of Ottawa

Practical math and the code to do it, for Neuroscientists

PCA, t-SNE, UMAP, Fourier, and other concepts applied to neuroscience data.

Classification of events in Neuronal Dynamics

Time series applications of Deep Learning


Background

Current pharmacotherapies for depression and anxiety have problematic disadvantages, the most important being high resistance in the population. Novel treatments such as the hallucinogens (I.E. LSD, Psilocybin (Psilocin), Ketamine), while robust, possess their own weaknesses such as the potential for abuse and the strain of hallucinogenic side-effects on treatment facility infrastructure. In recent years there has been a push to find novel, so-called next-generational psychedelic treatments that retain the positive anti-depression or anxiolytic properties with out the hallucinogenic side-effects. In the lab of Dr. Argel Aguilar Valles, we work with REDACTED, a non-hallucinogenic analogue of REDACTED which is showing promise as a novel therapeutic for REDACTED.

Currently, we use chronic variable stress assays, next-generational sequencing, and immunofluorescent imaging to investigate the effects of next-generation psychedelics on depression-like behavioural and neurogenesis in a mouse model of depression.

Education

  • Post-Doctoral Fellow, Aguilar Valles Lab, Carleton U
  • Ph.D. Collaborative Neuroscience Program, Guelph U
  • M.Sc. Biological Sciences, Brock U
  • Honors B.Sc. Biology, UofT

CONTACT

For questions or collaborations, reach out to me!

PUBLICATIONS

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vernlewis@cunet.carleton.ca